Aspirnaut™ Co-Authorships
Aspirnauts help expand the leading edge of new knowledge by conducting discovery science research. High school, undergraduate, and graduate students have been recognized as co-authors of scientific publications. One publication featured over 80 Aspirnaut co-authors in the leading journal Proceedings of the National Academy of Sciences (PNAS).
2023
The role of learned song in the evolution and speciation of Eastern and Spotted towhees
bioRxiv | May 16 2023
Defining mitochondrial cristae morphology changes induced by aging in brown adipose tissue
Advanced Biology | August 2023
Collagen IV of basement membranes: III. Chloride pressure is a primordial innovation that drives and maintains the assembly of scaffolds
JBC | November 2023
2021
Collagen IVα345 dysfunction in glomerular basement membrane diseases. III. A functional framework for α345 hexamer assembly
Journal of Biological Chemistry | January - June 2021
Collagen IVα345 dysfunction in glomerular basement membrane diseases. I. Discovery of a COL4A3 variant in familial Goodpasture’s and Alport diseases
Journal of Biological Chemistry, | January - June, 2021
ELAVL1 primarily couples mRNA stability with the 3′ UTRs of interferon-stimulated genes
Cell Reports | May 25, 2021
2020
Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies
Nature Medicine | January 13, 2020 | pages 26,98-109
Cotranslational folding stimulates programmed ribosomal frameshifting in the alphavirus structural polyprotein
Journal of Biological Chemistry, | January 17, 2020
Chronic femoral diaphyseal osteomyelitis with radiographs initially concerning for Paget disease of the bone
Radiology Case Reports | April 2020 | pages 344-348
Clostridioides difficile proline fermentation in response to commensal clostridia
ScienceDirect | June, 2020 | Volume 63
EGF Receptor–Mediated FUS Phosphorylation Promotes Its Nuclear Translocation and Fibrotic Signaling
Journal of Cell BIology | September 7, 2020
2019
Aspirnaut: a Rural High School Pipeline to Increase Diversity in STEM
Nature Reviews Nephrology | August 8, 2019 | pages 591-592
CysLT1 receptor antagonists pranlukast and zafirlukast inhibit LRRC8-medidated volume regulated anion channels independently of the receptor
Am J Physiol Cell Physiol | October 7, 2019 | pages 857-866
Discovery and characterization of 2-nitro-5-(4-(phenylsulfonyl)piperazin-1-yl)-N-(pyridine-4-ylmethyl) anilines as novel inhibitors of the Aedes aegypti Kir 1 (AeKir1) channel
ACS Infectious Diseases | March 4, 2019 | pages 5,6,917-931
Changes in urinary metabolome related to body fat involved intermediates of choline processing by gut microbiota
Heliyon | April 11, 2019
Cotranslational folding stimulates programmed ribosomal frameshifting in the alphavirus structural polyprotein
bioRxiv | 2019
A chloride ring is an ancient evolutionary innovation mediating the assembly of the collagen IV scaffold of basement membranes
J Biol Chem | March 28, 2019 | pages 294:7968-7981
Respiratory heterogeneity shapes biofilm formation and host colonization in uropathogenic Escherichia coli
mBio | April 2, 2019
2018
Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: differential effects on topoisomerase Iiα and Iiβ
Bioorganic & Medicinal Chemistry Letters | September 15, 2018
| pages 2961-2968
Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA
Nucleic Acids Research | April 20, 2018 | pages 3458-3467
Salt-bridge modulates differential calcium-mediated ligand binding to integrin α1- and α2-I domains
Scientific Reports | February 3, 2018 | pages 258-271
Unicellular ancestry and mechanisms of diversification of Goodpasture-antigen binding
protein
The Journal of biological chemistry | November 1, 2018
Discovery, characterization, and effects on renal fluid and electrolyte excretion of the Kir4.1 postassium channel pore blocker, VU0134992
Molecular Pharmacology | August 2018 | pages 926-937
Effect of Temperature on the release of Proterometra macrostoma (Trematoda: Digenea) cercariae from their snail intermediate host, Pleurocera semicarinata (Gastropoda: Pleuroceridae) at North Elkhorn Creek, Kentucky
Comparative Parasitology, | July 1, 2018 | pages 202-207
2017
Blocking TGF-β and β-catenin epithelial crosstalkexacerbates CKD
Journal of the American Society of Nephrology | December 28, 2017 | pages 3490-3503
Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice
Nature Communications | September 29, 2017 | Article 750
Discoidin domain receptor 1 kinase activity is required for regulating collagen IV synthesis
Matrix Biology | January 2017 | pages 258-271
Embryo implantation triggers dynamic spatiotemporal expression of the basement membrane toolkit during uterine reprogramming
Matrix Biology | January 2017 | pages 931-939
2016
Basement membrane ultrastructure and component localization data from uterine tissues during early mouse pregnancy
Data in Brief | November 5, 2016 | pages 931-939
A pH-mediated topological switch within the n-terminal domain of humnan caveolin-3
Biophysical Journal | June 7, 2016 | pages 2475-2485
Extracellular chloride signals collagen IV network assembly during basement membrane formation
JCB | May 23, 2016 | pages 479-494
2015
Pyridoxamine protects proteins from damage by hypohalous acids in vitro and in vivo
Free Radical Biology & Medicine | December 2015 | pages 83-90
The Ancient Immunoglobulin Domains of Peroxidasin Are Required to Form Sulfilimine Cross-links in Collagen IV
Journal of Biological Chemistry | August 28, 2015 | pages 21741-21748
5′-O-Alkylpyridoxamines: Lipophilic Analogues of Pyridoxamine Are Potent Scavengers of 1,2-Dicarbonyls
Chemical Research in Toxicology | July 20, 2015 | pages 1469-1475
Hypohalous acids contribute to renal extracellular matrix damage in experimental diabetes
Diabetes | June 2015 | pages 2242-2253
Alterations of urinary metabolite profile in model diabetic nephropathy
Biochemical and biophysical research communications | January 9, 2015 | pages 610-614
2014
Supramolecular organization of the α121-α565 collagen IV network
JBC | September 12, 2014 | pages 25601-25610
TRIP/NOPO E3 ubiquitin ligase promotes ubiquitylation of DNA polymerase eta
Development | January 2014 | pages 1332-1341
A unique covalent bond in basement membrane is a primordial innovation for tissue evolution
PNAS | January 7, 2014 | pages 331-336
2012
Peroxidasin forms sulfilimine chemical bonds using hypohalous acids in tissue genesis
Nature Chemical Biology | September 2012 | pages 784-790
2011
Glucose autoxidation induces functional damage to proteins via modification of critical arginine residues
Biochemical and Biophysical Research Communications | August 5, 2011 | pages 574-579
Glucose autoxidation induces functional damage to proteins via modification of critical arginine residues
Biochemistry Vol 50, Issue 27 | July 12, 2011 | pages 6102-6112